NIHR Biomedical Research Centre for Mental Health: Computational Biology
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Bioinformatic Software Tools

This page documents a collection of bioinformatic tools which have been written by our group.

cmpfastq

A simple perl program that allows the user to compare QC filtered fastq files. It will identify “paired” and “un-paired” reads and write out 2 results files for each filtered paired-end fastq file.

cmpfastq_pe

A modified version of cmpfastq that can handle CASAVA v1.8 headers and uses significantly less memory but can only handle files from the same flowcell lane with the same index tag

Forge

FORGE is tool to perform gene based Genome-Wide Association Studies. It allows to combine information from different genetic variants into a single statistic. We have shown it provides additional power to detect true disease loci and it is useful to perform pathway or network analyses.

ForgeWeb

This is a web front-end to the Forge application above.